1380332-26-2

Upstream product

• 1380332-38-6 C₁₃H₁₈O₂ 
• 22508-64-1 4-methyl-4-penten-1-ol 
• 4911-54-0 ethyl 4-methyl-4-pentenoate 
• 73541-16-9 5-iodo-2-methylpent-1-en 
• 25163-50-2 4-methyl-4-pentenyl-1-tosylate 

Relevant academic research and scientific papers

Intramolecular condensation via an o-quinone methide: Total synthesis of (±)-heliol

An acid-catalyzed intramolecular [4 + 2] cycloaddition of a non-natural bisabolene is reported. The key cyclocondensation was developed to access cyclic sesquiterpenes from linear phenolic precursors by generating a reactive o-quinone methide intermediate to initiate a cascade reaction. The new method was applied to the first total synthesis of (±)-heliol.