1380359-52-3Relevant academic research and scientific papers
Chemoenzymatic synthesis of highly enantiomerically enriched secondary alcohols with a thiazolic core
Pop, Laura,Lassalas, Pierrik,Bencze, Laszlo Csaba,Tosa, Monica Ioana,Nagy, Botond,Irimie, Florin Dan,Hoarau, Christophe
, p. 474 - 481 (2012)
Stereoselective preparative enzymatic acylation and hydrolysis/methanolysis of various C-substituted rac-thiazol-2-yl-methanols were achieved for the preparation of enantiopure or enantiomerically enriched, naturally occurring 2-hydroxymethylthiazoles. The absolute configurations of the resulting secondary alcohols were determined by a detailed 1H NMR study of Mosher's derivatives.
