138036-14-3

Basic information

• Product Name: Pentanedioic acid, 2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, 5-methyl ester, (S)-
• CAS NO: 138036-14-3
• Molecular Formula: C14H13NO6
• Molecular Weight: 291.26
• Mol File: 138036-14-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Pentanedioic acid, 2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, 5-methyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanedioic acid, 2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, 5-methyl ester, (S)-(138036-14-3)
• EPA Substance Registry System: Pentanedioic acid, 2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, 5-methyl ester, (S)-(138036-14-3)

Safety Data

• Hazardous Substances Data: 138036-14-3(Hazardous Substances Data)

Upstream product

• 1499-55-4 DL-glutamic acid-5-methyl ester 
• 85-44-9 phthalic anhydride 
• 1499-55-4 L-glutamic acid 5-methyl ester 

Downstream Products

• 3081-61-6 N-ethyl-L-glutamine 
• 1499-55-4 DL-glutamic acid-5-methyl ester 
• 119278-26-1 N¹-(4-ethoxycarbonyl-phenyl)-N²,N²-phthaloyl-L-isoglutamine-methyl ester 
• 109932-21-0 N¹-phenyl-N²,N²-phthaloyl-L-isoglutamine-methyl ester 

Relevant articles and documents

Silver-Catalyzed Efficient Synthesis of Oxindoles and Pyrroloindolines via α-Aminoalkylation of N-Arylacrylamides with Amino Acid Derivatives

α-Aminoalkylation of N-arylacrylamides with amino acid derivatives was achieved by silver-catalysis in moderate to high yields. The reaction provides an efficient strategy for the synthesis of functionalized oxindoles, and is suitable for a wide range of N-arylacrylamides and amino acids, both of which are inexpensive and readily available. The oxindoles obtained were readily transformed into densely functionalized pyrroloindolines by deprotection and cyclization in one pot.

Direct, visible light-sensitized benzylic C[sbnd]H fluorination of peptides using dibenzosuberenone: selectivity for phenylalanine-like residues

A visible light-sensitized benzylic sp3C[sbnd]H fluorination protocol using dibenzosuberenone (5?mol?%) and Selectfluoris optimized for the direct functionalization of phenylalanine-like residues in short chain peptides. Amino acids, dipeptides, and tripeptides undergo benzylic fluorination with remarkable regioselectivity in the presence of protected basic, acidic, and nonpolar side chains (including those with tertiary sites). Additionally, protecting group compatibility, a gram scale application, and competition experiments were explored.