138041-99-3Relevant academic research and scientific papers
Directed ortho Metallation Studies on Podocarpic Acid Derivatives: Advantageous Use of a LICKOR Base
Cambie, Richard C.,Higgs, Paul I.,Lee, Kee Chee,Metzler, Michael R.,Rutledge, Peter S.,at al.
, p. 1465 - 1477 (2007/10/02)
Methyl 13-(N,N-diethylcarbamoyl)-12-methoxypodocarpa-8,11,13-trien-19-oate (2), 13-(N,N-diethylcarbamoyl)-12,19-dimethoxypodocarpa-8,11,13-triene (8) and N,N-diethyl-2-methoxy-4,5-dimethylbenzamide (15) were prepared for studies involving lithiation directed ortho to the tertiary amide group, in which the use of a LICKOR base was advantageous.Some dynamic features of the n.m.r. spectra of the amides are discussed.Oxazoline derivatives of both the monocyclic and diterpenoid compounds were synthesized.
