138046-43-2 Usage
Uses
1. Used in Pharmaceutical Industry:
N-Cycloheptyl-N-(9H-fluoren-2-ylmethyl)-N'-(2,4,6-trimethylphenyl)urea is used as an Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor for its ability to regulate cholesterol metabolism and reduce the risk of atherosclerosis. As an ACAT inhibitor, YM 750 can help lower cholesterol levels in the body, which is particularly beneficial for individuals with hypercholesterolemia or at risk of developing atherosclerotic cardiovascular diseases.
2. Used in Cardiovascular Health:
N-Cycloheptyl-N-(9H-fluoren-2-ylmethyl)-N'-(2,4,6-trimethylphenyl)urea is used as a hypocholesterolaemic agent for its potential to lower cholesterol levels in the body. By inhibiting the enzyme ACAT, YM 750 can help reduce the formation of cholesterol esters, which are known to contribute to the development of atherosclerosis and other cardiovascular diseases.
3. Used in Antiatherosclerotic Applications:
N-Cycloheptyl-N-(9H-fluoren-2-ylmethyl)-N'-(2,4,6-trimethylphenyl)urea is used as an antiatherosclerotic agent for its ability to prevent the formation of atherosclerotic plaques in the arteries. By inhibiting ACAT, YM 750 can help reduce the accumulation of cholesterol in the arterial walls, thereby decreasing the risk of atherosclerosis and its associated complications, such as heart attacks and strokes.
Check Digit Verification of cas no
The CAS Registry Mumber 138046-43-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,0,4 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 138046-43:
(8*1)+(7*3)+(6*8)+(5*0)+(4*4)+(3*6)+(2*4)+(1*3)=122
122 % 10 = 2
So 138046-43-2 is a valid CAS Registry Number.
138046-43-2Relevant academic research and scientific papers
Urea derivatives and salts thereof in method for inhibiting the ACAT enzyme
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, (2008/06/13)
Urea derivatives of the general formula (I) STR1 and salts thereof, pharmaceutical compositions containing the same, and methods for producing the same are disclosed. The urea derivatives of the general formula (I) and salts thereof are novel compounds ha
