1380611-72-2

Upstream product

• 74879-43-9 (R)-N-benzylidene-2-hydroxy-1-phenylethylamine 
• 4392-24-9 Cinnamyl bromide 

Downstream Products

• 1380611-73-3 (1R,2R)-1,2-diphenylbut-3-en-1-amine 
• 1380611-82-4 C₃₅H₃₁N 
• 1380611-79-9 (2R,3R)-2,3-diphenylpyrrolidine 

Relevant academic research and scientific papers

Switching regioselectivity in the allylation of imines by N-side chain tuning

A spectacular inversion of α- to γ-regioselectivity in the allylzincation of imines can be achieved by fine-tuning of the N-side chain. This approach allows easy preparation of regioisomeric amines, in racemic as well as enantiopure forms. The usefulness of the method is illustrated by the parallel asymmetric syntheses of 2,3- and 2,5-diphenylpyrrolidines.