1380672-67-2

Upstream product

• 95-51-2 o-chloroaniline 
• 40019-21-4 3-methyl-[1,2,4]oxadiazole-5-carboxylic acid ethyl ester 

Downstream Products

• 1380672-03-6 4-(5-((E)-2-(4-(2-chlorophenyl)-5-(3-methyl-1,2,4-oxadiazol-5-yl)-4H-1,2,4-triazol-3-yl)vinyl)-1,3,4-oxadiazol-2-yl)-2-methoxypyridine 
• 1380672-68-3 N-amino-N'-(2-chlorophenyl)-3-methyl-1,2,4-oxadiazole-5-carboxamidine 

Relevant academic research and scientific papers

TRIAZOLE DERIVATIVES AS WNT SIGNALING PATHWAY INHIBITORS

The present invention relates to compounds of formula (I), to processes for their preparation, to pharmaceutical formulations containing such compounds and to their use in therapy: Such compounds find particular use in the treatment and/or prevention of conditions or diseases which are affected by over-activation of signaling in the Wnt pathway and increased presence of nuclear β-catenin. For example, these may be used in preventing and/or retarding proliferation of tumor cells and metastasis, for example carcinomas such as colon carcinomas.