1380778-65-3

Upstream product

• 16848-19-4 3-amino-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 1380778-62-0 (3aR,5R,6S,6aR)-5-ethynyl-6-methylamino-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole 
• 34897-85-3 o-azidobenzoyl chloride 
• 1380778-61-9 (3aR,5R,6S,6aR)-5-ethynyl-6-(N-4-nitrobenzenesulfonyl-N-methylamino)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole 
• 1380778-59-5 3-deoxy-3-(N-4-nitrobenzenesulfonyl-N-methylamino)-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 1380778-56-2 3-deoxy-3-(N-4-nitrobenzenesulfonylamino)-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 

Relevant academic research and scientific papers

Design and synthesis of 1,2,3-triazole-fused chiral medium-ring benzo-heterocycles, scaffolds mimicking benzolactams

Based on amide-triazole bioequivalence principle, 1,2,3-triazole-fused chiral medium ring benzo-heterocycles capable of mimicking benzolactams were designed. Their syntheses were accomplished by cycloaddition of different sugar-derived azidoalkynes. While triazole-fused eight-membered benzo-heterocycles were formed by exclusive intramolecuclar [3 + 2] cycloaddition, attempted preparation of seven-membered analogues led to some intermolecular cycloaddition resulting in a dimeric macrocyclic product, in addition to intramolecular cycloaddition furnishing the expected heterocycle.