138090-71-8

Upstream product

• 17507-56-1 ethyl 2-diazo-2-(diethoxyphosphoryl)acetate 
• 822-67-3 Cyclohex-2-enol 

Downstream Products

• 138090-70-7 2-(Cyclohex-2-enyloxy)-2-(diethoxy-phosphoryl)-3-dimethylamino-propionic acid ethyl ester 
• 1451368-65-2 ethyl 2-(cyclohex-1-en-1-yl)-2-diethoxyphosphoryloxyacetate 
• 138090-78-5 {2-Cyclohex-2-enyl-1-[(2,4-dinitro-phenyl)-hydrazono]-ethyl}-phosphonic acid diethyl ester 
• 138090-69-4 {2-Cyclohex-2-enyl-1-[(2,4-dinitro-phenyl)-hydrazono]-ethyl}-phosphonic acid diethyl ester 
• 138090-76-3 [1-(Cyclohex-2-enyloxy)-vinyl]-phosphonic acid diethyl ester 
• 138090-77-4 (2-Cyclohex-2-enyl-acetyl)-phosphonic acid diethyl ester 

Relevant academic research and scientific papers

Bronsted base catalyzed [2,3]-Wittig/phospha-Brook tandem rearrangement sequence

A Bronsted base catalyzed rearrangement reaction of 2-allyloxy-2-phosphonoacetate derivatives was developed. This reaction proceeded via a [2,3]-Wittig rearrangement followed by a phospha-Brook rearrangement. This is the first example of a catalytic [2,3]-Wittig rearrangement initiated by a Bronsted base.

Phosphonate Analogues of Chorismic Acid: Synthesis and Evaluation as Mechanism-Based Inactivators of Chorismate Mutase

The mechanism of chorismate mutase, the enzyme which catalyzes the Claisen arrangement of chorismic to prephenic acid, remains a fascinating area for bioorganic research.This paper describes the enantioselective synthesis of phosphonochorismic acids 3 and