13816-22-3

Upstream product

• 1370477-93-2 3-(4,5-dihydrothiazol-2-yl)benzonitrile 
• 1016928-35-0 1,3-bis(4,5-dihydrothiazol-2-yl)benzene 
• 626-17-5 benzene-1,3-dicarbonitrile 
• 3030-54-4 1,3-benzenedicarboxylic acid dithioamide 
• 15873-56-0 monochloroacetaldehyde hydrate 

Downstream Products

• 1613643-11-0 C₂₈H₂₆N₄S₂ 

Relevant academic research and scientific papers

POLYCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME

The present disclosure provides compounds, or pharmaceutically acceptable salts thereof, for inhibiting the growth of a microbe; treating a mammal having a microbial infection, malaria, mucositis, an ophthalmic infection, an otic infection, a cancer, or a Mycobacterium infection; killing or inhibiting the growth of a Plasmodium species; inhibiting the growth of a Mycobacterium species; modulating an immune response in a mammal; or antagonizing unfractionated heparin, low molecular weight heparin, or a heparin/low molecular weight heparin derivative.

DDQ-induced dehydrogenation of heterocycles for c-c double bond formation: Synthesis of 2-thiazoles and 2-oxazoles

Strong as an Ox: 2-Thiazoles and 2-oxazoles are formed by oxidation of 2-thiazolines and 2-oxazolines without requiring substituents at the C4 and C5 positions. DDQ plays an important role as the oxidant in this transformation and metal is unnecessary. This general procedure shows good functional group tolerance and provides a wide variety of 2-thiazoles and 2-oxazoles in moderate to excellent yields.