138167-90-5

Upstream product

• 87351-92-6 α-<methyl>-3,4-dimethoxybenzyl alcohol 
• 87351-99-3 1,2,3,4-tetrahydro-4-(3,4-dimethoxyphenyl)-2-methylisoquinoline-8-carboxylic acid hydrochloride 
• 552-89-6 2-nitro-benzaldehyde 
• 87351-90-4 α-<methyl>-3,4-dimethoxybenzyl alcohol 
• 87351-89-1 α-<<(2-nitrobenzyl)amino>methyl>-3,4-dimethoxybenzyl alcohol 
• 87351-88-0 α-<<(2-nitrobenzylidene)amino>methyl>-3,4-dimethoxybenzyl alcohol 
• 15471-89-3 α-(aminomethyl)-3,4-dimethoxybenzyl alcohol hydrochloride 

Downstream Products

• 87419-65-6 (R)-(-)-8-amino-1,2,3,4-tetrahydro-4-(3,4-dihydroxyphenyl)-2-methylisoquinoline 
• 87419-66-7 (S)-(+)-8-amino-1,2,3,4-tetrahydro-4-(3,4-dihydroxyphenyl)-2-methylisoquinoline 
• 87419-69-0 (S)-4-(3,4-Dimethoxy-phenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine 
• 87419-67-8 (R)-4-(3,4-Dimethoxy-phenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine 
• 69275-19-0 3',4'-Dihydroxynomifensin 

Relevant academic research and scientific papers

Synthesis, resolution, absolute stereochemistry, and enantioselectivity of 3',4'-dihydroxynomifensine

3',4'-Dihydroxynomifensine, 8-amino-1,2,3,4-tetrahydro-4-(3,4-dihydroxyphenyl)-2-methylisoquinoline (1a), is an agonist of dopamine receptors in central and peripheral systems. Since this dopamine receptor agonist bears an asymmetric center at position 4,

Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines

4-Phenyl-1,2,3,4-tetrahydroisoquinolines whose structures have two hydroxy groups substituted at the 3,4-position on the 4-phenyl ring have been found to have renal vasodilating activity upon internal administration. The active ingredients are prepared by cyclizing N-(2-substituted benzyl)-1-(3,4-dimethoxyphenyl)-aminoethanol using either a Lewis acid or an acid cyclizing agent followed by demethylation at the 3,4-dimethoxyphenyl moiety.