1381778-21-7

Basic information

• Product Name: 1-((2-tert-butyloxazol-5-yl)methyl)-4-phenyl-1,2,4-triazolidine-3,5-dione
• Synonyms: 1-((2-tert-butyloxazol-5-yl)methyl)-4-phenyl-1,2,4-triazolidine-3,5-dione
• CAS NO: 1381778-21-7
• Molecular Weight: 314.344
• Mol File: 1381778-21-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-((2-tert-butyloxazol-5-yl)methyl)-4-phenyl-1,2,4-triazolidine-3,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((2-tert-butyloxazol-5-yl)methyl)-4-phenyl-1,2,4-triazolidine-3,5-dione(1381778-21-7)
• EPA Substance Registry System: 1-((2-tert-butyloxazol-5-yl)methyl)-4-phenyl-1,2,4-triazolidine-3,5-dione(1381778-21-7)

Safety Data

• Hazardous Substances Data: 1381778-21-7(Hazardous Substances Data)

Upstream product

• 4233-33-4 4-Phenyl-1,2,4-triazolidine-3,5-dione 
• 1187846-20-3 2-tert-butyl-5-methylene-4,5-dihydrooxazole 
• 178320-73-5 2,2-dimethyl-N-(prop-2-ynyl)propionamide 

Relevant articles and documents

Gold catalysis: One-pot alkylideneoxazoline synthesis/Alder-ene reaction

Based on the gold-catalyzed synthesis of methyleneoxazolines, a one-pot combination with an Alder-ene reaction was developed. For azodicarboxylates, good to very good yields (51-99%) of the oxazolemethylhydrazinedicarboxylates were achieved with 3 mol% of the Gagosz catalyst, [Ph3PAuNTf 3]. In a less-selective reaction, 4-phenyl-3H-1,2,4-triazol-3,5(4H)- dione gave lower yields (41-49%) of the corresponding oxazolemethylphenyltriazolidinediones. Overall, five new bonds were formed. Tetracyanoethylene afforded a cyclobutane derivative through a [2+2] cycloaddition reaction at -40°C, but only 45% of the spiro compound was obtained. The less-readily available KITPHOS ligands on gold gave even higher yields at lower catalyst loadings (2a mol%), but longer reaction times were required. Copyright