1381799-98-9Relevant academic research and scientific papers
Synthesis of chiral helical 1,3-oxazines
Talele, Harish R.,Sahoo, Sibaprasad,Bedekar, Ashutosh V.
supporting information; experimental part, p. 3166 - 3169 (2012/08/28)
A series of novel 1,3-oxazines were prepared to construct a helical framework. The 1,3-oxazine attached to the phenanthrene unit showed a small bite angle θ (～12°), while the units attached to [4]helicene showed a larger θ (～35°) and exhibited helical isomers at ambient conditions. The diastereomers of the third type of helicene-like bis-oxazine attached to binaphthyl were easily separable and showed good thermal stability. All four diastereomers of bis-helicene were synthesized, and their absolute configuration was established.
