1381848-20-9

Basic information

• Product Name: methyl 4-(3-(4-methoxyphenyl)guanidino)benzoate
• CAS NO: 1381848-20-9
• Molecular Weight: 299.329
• Mol File: 1381848-20-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 4-(3-(4-methoxyphenyl)guanidino)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(3-(4-methoxyphenyl)guanidino)benzoate(1381848-20-9)
• EPA Substance Registry System: methyl 4-(3-(4-methoxyphenyl)guanidino)benzoate(1381848-20-9)

Safety Data

• Hazardous Substances Data: 1381848-20-9(Hazardous Substances Data)

Upstream product

• 696-62-8 para-iodoanisole 
• 122228-09-5 N-(p-methoxycarbonylphenyl)guanidine 

Relevant articles and documents

Synthesis of symmetrical and unsymmetrical N, N ′-diaryl guanidines via copper/N-methylglycine-catalyzed arylation of guanidine nitrate

CuI/N-methylglycine-catalyzed coupling reaction of guanidine nitrate with both aryl iodides and bromides takes place at 70-100 °C, affording symmetrical N,N′-diaryl guanidines with good to excellent yields. Unsymmetrical N,N′-diaryl guanidines can be assembled via monoarylation of guanidine nitrate with aryl iodides bearing a strong electron-withdrawing group and subsequent coupling with another aryl iodide.