1381848-67-4

Upstream product

• 1381848-65-2 C₁₇H₃₆O₂Si 
• 1381848-64-1 C₁₁H₂₂O₂ 
• 1381848-66-3 C₁₇H₃₈O₄Si 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 1381848-62-9 C₁₆H₃₄O₂Si 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 870-63-3 prenyl bromide 

Downstream Products

• 1381848-68-5 C₂₇H₄₂O₄Si 
• 1381848-69-6 C₂₇H₃₈O₄Si 
• 1381848-71-0 (4R,6R)-6-((S)-4-((tert-butyldiphenylsilyl)oxy)-2-methyl-3-((triethylsilyl)oxy)butan-2-yl)-4-methyltetrahydro-2H-pyran-2-one 
• 1381848-73-2 (2R,4R)-2-((S)-4-((tert-butyldiphenylsilyl)oxy)-2-methyl-3-((triethylsilyl)oxy)butan-2-yl)-4-methyl-3,4-dihydro-2H-pyran-6-yl trifluoromethanesulfonate 
• 1381848-75-4 C₅₉H₉₆O₇Si₃ 
• 1381848-79-8 (2R,3S,4R,6R)-6-((S)-4-((tert-butyldiphenylsilyl)oxy)-2-methyl-3-((triethylsilyl)oxy)butan-2-yl)-2-methoxy-2-(((2S,4S,5S,6S)-6-(2-((4-methoxybenzyl)oxy)ethyl)-5-methyl-4-((triisopropylsilyl)oxy)-tetrahydro-2H-pyran-2-yl)methyl)-4-methyltetrahydro-2H-pyran-3-ol 
• 1381848-80-1 (2R,3R,4R,6R)-6-((S)-4-((tert-butyldiphenylsilyl)oxy)-2-methyl-3-((triethylsilyl)oxy)butan-2-yl)-2-methoxy-2-(((2S,4S,5S,6S)-6-(2-((4-methoxybenzyl)oxy)ethyl)-5-methyl-4-((triisopropylsilyl)-oxy)tetrahydro-2H-pyran-2-yl)methyl)-4-methyltetrahydro-2H-pyran-3-ol 
• 1381848-82-3 (2R,4R,6R)-6-((S)-4-((tert-butyldiphenylsilyl)oxy)-2-methyl-3-((triethylsilyl)oxy)butan-2-yl)-2-methoxy-2-(((2S,4S,5S,6S)-6-(2-((4-methoxybenzyl)oxy)ethyl)-5-methyl-4-((triisopropylsilyl)oxy)tetrahydro-2H-pyran-2-yl)methyl)-4-methyldihydro-2H-pyran-3(4H)-one 
• 1381848-83-4 (2R,4R,6R)-6-((S)-4-((tert-butyldiphenylsilyl)oxy)-3-hydroxy-2-methylbutan-2-yl)-2-(((2S,4S,5S,6S)-6-(2-hydroxyethyl)-5-methyl-4-((triisopropylsilyl)oxy)tetrahydro-2H-pyran-2-yl)methyl)-2-methoxy-4-methyldihydro-2H-pyran-3(4H)-one 
• 1381848-85-6 2-((2S,3S,4S,6S)-6-(((2R,4R,6R)-6-((S)-4-((tert-butyldiphenylsilyl)oxy)-3-hydroxy-2-methylbutan-2-yl)-2-methoxy-4-methyl-3-oxotetrahydro-2H-pyran-2-yl)methyl)-3-methyl-4-((triisopropylsilyl)oxy)tetrahydro-2H-pyran-2-yl)acetic acid 
• 1381848-86-7 (1S,3R,5R,7R,9S,13S,14S,15S)-9-(((tert-butyldiphenylsilyl)oxy)methyl)-3-methoxy-5,8,8,14-tetramethyl-15-((triisopropylsilyl)oxy)-10,17,18-trioxatricyclo[11.3.1.13,7]octadecane-4,11-dione 
• 1381848-84-5 C₅₄H₈₄O₉Si₂ 

Relevant academic research and scientific papers

Total synthesis of (-)-polycavernoside A: Suzuki-Miyaura coupling approach

A total synthesis of (-)-polycavernoside A, a marine lethal toxin isolated from the edible alga Gracilaria edulis, has been achieved via a convergent approach. The synthesis is highlighted by catalytic asymmetric syntheses of the two key fragments and their union through Suzuki-Miyaura coupling and Keck macrolactonization.