1381859-88-6

Basic information

• Product Name: (S)-tert-butyl 1-[(S)-2-(ethoxycarbonyl)-1-phenylallyl]-3-oxo-1,3-dihydroisobenzofuran-1-carboxylate
• Synonyms: (S)-tert-butyl 1-[(S)-2-(ethoxycarbonyl)-1-phenylallyl]-3-oxo-1,3-dihydroisobenzofuran-1-carboxylate
• CAS NO: 1381859-88-6
• Molecular Weight: 422.478
• Mol File: 1381859-88-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-tert-butyl 1-[(S)-2-(ethoxycarbonyl)-1-phenylallyl]-3-oxo-1,3-dihydroisobenzofuran-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 1-[(S)-2-(ethoxycarbonyl)-1-phenylallyl]-3-oxo-1,3-dihydroisobenzofuran-1-carboxylate(1381859-88-6)
• EPA Substance Registry System: (S)-tert-butyl 1-[(S)-2-(ethoxycarbonyl)-1-phenylallyl]-3-oxo-1,3-dihydroisobenzofuran-1-carboxylate(1381859-88-6)

Safety Data

• Hazardous Substances Data: 1381859-88-6(Hazardous Substances Data)

Upstream product

• 708-14-5 phthalide-3-carboxylic acid 
• 129881-51-2 acid chloride of 1-oxo-1,3-dihydroisobenzofuran-3-carboxylic acid 
• 1374450-07-3 tert-butyl 3-oxo-1,3-dihydroisobenzofuran-1-carboxylate 
• 87-41-2 2-benzofuran-1(3H)-one 

Relevant articles and documents

Highly enantioselective regiodivergent allylic alkylations of MBH carbonates with phthalides

Phthalides were used for the first time in the allylic alkylation reactions with MBH carbonates for the creation of chiral 3,3-disubstituted phthalides. Highly enantioselective regiodivergent synthesis of γ-selective or β-selective allylic alkylation products was achieved by employing bifunctional chiral phosphines or multifunctional tertiary amine-thioureas as the catalyst, respectively. It was demonstrated that proper selection of catalysts and reaction conditions would differentiate an SN2′- SN2′ pathway and an addition-elimination process, yielding different regioisomers of the allylic alkylation products in a highly enantiomerically pure form.