1381861-94-4

Basic information

• Product Name: Biotin-PEG3-propionic hydrazide
• Synonyms: Biotin-PEG3-propionic hydrazide;Biotin-PEG3-hydrazide;Biotin-PEG3-HZ
• CAS NO: 1381861-94-4
• Molecular Formula: C19H35N5O6S
• Molecular Weight: 461.5761
• Product Categories: PEGylated Biotin
• Mol File: 1381861-94-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 813.7±65.0 °C(Predicted)
• Appearance: /
• Density: 1.210±0.06 g/cm3(Predicted)
• PKA: 12.82±0.35(Predicted)
• CAS DataBase Reference: Biotin-PEG3-propionic hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Biotin-PEG3-propionic hydrazide(1381861-94-4)
• EPA Substance Registry System: Biotin-PEG3-propionic hydrazide(1381861-94-4)

Safety Data

• Hazardous Substances Data: 1381861-94-4(Hazardous Substances Data)

Usage

Description

Biotin-PEG3-propionic hydrazide is a hydrazide-activated biotinylation reagent specifically designed for the labeling of glycoproteins and carbohydrate-containing compounds that possess oxidizable sugars or aldehydes. This versatile molecule is characterized by its ability to form semi-permanent hydrazone bonds with aldehyde groups, allowing for stable and selective biotinylation.

Uses

Used in Biomedical Research:
Biotin-PEG3-propionic hydrazide is used as a labeling agent for the detection and analysis of glycoproteins in various biomedical research applications. The biotinylation process enhances the ability to track and study these proteins, which play crucial roles in numerous biological processes.
Used in Diagnostic Applications:
In the field of diagnostics, Biotin-PEG3-propionic hydrazide is employed as a key component in the development of assays and tests for the identification of specific glycoproteins. The biotinylated proteins can be easily detected using streptavidin-conjugated detection systems, providing a sensitive and reliable method for disease diagnosis and monitoring.
Used in Drug Development:
Biotin-PEG3-propionic hydrazide is utilized as a tool in drug development for the identification and characterization of potential drug targets, particularly glycoproteins involved in various diseases. The biotinylation of these targets allows for their isolation and further study, contributing to the understanding of their role in disease pathology and the development of targeted therapeutics.
Used in Analytical Techniques:
This biotinylation reagent is also used in various analytical techniques, such as mass spectrometry and protein microarrays, to study the structure, function, and interactions of glycoproteins. The biotinylation process facilitates the selective enrichment and detection of these proteins, providing valuable insights into their biological roles and potential applications in research and medicine.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Biotin-PEG3-propionic hydrazide is used as a biotinylation agent for the development of drug conjugates and targeted drug delivery systems. The biotinylated molecules can be specifically recognized and bound by streptavidin or other biotin-binding proteins, enabling the selective delivery of therapeutic agents to desired cellular targets.