1381865-08-2Relevant articles and documents
Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors
Chu, Lin,Armstrong, Helen M.,Chang, Linda L.,Cheng, Amy F.,Colwell, Lawrence,Cui, Jisong,Evans, Jilly,Galka, Amy,Goulet, Mark T.,Hayes, Nancy,Lo, Jane,Menke, John,Ok, Hyun O.,Ondeyka, Debra L.,Patel, Minal,Quaker, Grace M.,Sings, Heather,Witkin, Stephanie L.,Zhao, Annie,Ujjainwalla, Feroze
, p. 4133 - 4138 (2012/07/03)
A search for a suitable replacement for the central norbornyl scaffold presented in the recently disclosed novel FLAP inhibitors is herein described, as well as the SAR study performed on the endo and exo-aryl groups.
