138194-60-2Relevant academic research and scientific papers
Facile synthesis of reagents containing a terminal maleimido ligand linked to an active ester
Nielsen,Buchardt
, p. 819 - 821 (2007/10/02)
Condensation of ω-amino acids with maleic anhydride to yield maleamino acids and subsequent esterification with N-hydroxysuccinimide, 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine, or pentafluorophenol to give the corresponding esters in a one pot procedure are described. The reagents can be isolated and purified without chromatography in 7-55% yields.
