138202-89-8Relevant academic research and scientific papers
Stereoselective synthesis of 3-fluoro azetidinones via the condensation of 2-fluoropropanethioate lithium enolate with imines
Ishihara,Ichihara,Yamanaka
, p. 255 - 262 (2007/10/02)
S-Phenyl-2-fluoropropanethioate (1) was treated with lithium diisopropylamide in THF at -78°C to give rise to the lithium enolate, which underwent stereoselective condensation with a variety of aldehyde imines (2) at room temperature to afford the corresp
The Stereoselective Synthesis of 3-Fluoro-azetidinones
Araki, Koichi,Wichtowski, John A.,Welch, John T.
, p. 5461 - 5464 (2007/10/02)
3-Fluoro-azetidinones were prepared by both the enolate-imine and ketene-imine condensation reactions.The reactions of fluorinated ketenes with imines were remarkably stereoselective forming products derived from lk reaction topicity.Key Words: β-Lactams;
