1382038-55-2

Upstream product

• 59887-89-7 7-hydroxy-4H-chromen-4-one 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 1348630-12-5 C₁₂H₈O₃ 
• 589-15-1 1-bromomethyl-4-bromobenzene 

Relevant academic research and scientific papers

Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry

Based on the advantages of natural products in new anti-cancer drug development, we synthesized a series of novel benzopyran-4-one derivatives and evaluated their in vitro anti-cancer activities. The bioassays showed that the majority of the resultant compounds exerted anti-tumor effect against six human cancer cell lines to various extents, which supported the rationale of the design. Compound 5s exhibited highest potency of all the synthesized compounds.