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1382182-73-1

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1382182-73-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1382182-73-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,8,2,1,8 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1382182-73:
(9*1)+(8*3)+(7*8)+(6*2)+(5*1)+(4*8)+(3*2)+(2*7)+(1*3)=161
161 % 10 = 1
So 1382182-73-1 is a valid CAS Registry Number.

1382182-73-1Downstream Products

1382182-73-1Relevant articles and documents

Synthesis and evaluation of 4- and 5-pyridazin-3-one phenoxypropylamine analogues as histamine-3 receptor antagonists

Becknell, Nadine C.,Lyons, Jacquelyn A.,Aimone, Lisa D.,Huang, Zeqi,Gruner, John A.,Raddatz, Rita,Hudkins, Robert L.

experimental part, p. 3880 - 3886 (2012/08/27)

A novel series of 4-pyridazin-3-one and 5-pyridazin-3-one analogues were designed and synthesized as H3R antagonists. Structure-activity relationship revealed the 5-pyridazin-3-ones 8a and S-methyl 8b had excellent human and rat H3R affinities, and acceptable pharmacokinetic properties. In vivo evaluation of 8a showed potent activity in the rat dipsogenia model and robust wake-promoting activity in the rat EEG/EMG model.

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