138240-65-0 Usage
Uses
Used in Pharmaceutical Industry:
Panipenem-betamipron is used as an antibiotic for the treatment of respiratory infections caused by a wide range of clinically important species of both Gram-positive and Gram-negative organisms, including Staph. aureus, E. faecalis, and P. aeruginose. Its potent antibacterial activity and efficacy in patients with severe infections and in children where other antibiotics were ineffective make it a valuable option in the treatment of respiratory infections.
Used in Renal Protection:
Panipenem-betamipron is used as a renal protective agent to prevent renal dysfunction associated with the use of antibiotics. The inclusion of betamipron, an organic anion transport inhibitor, in the drug formulation blocks the incorporation of panipenem into renal tubules, thus providing renal protection during the treatment of respiratory infections.
Originator
Sankyo (Japan)
Check Digit Verification of cas no
The CAS Registry Mumber 138240-65-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,2,4 and 0 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 138240-65:
(8*1)+(7*3)+(6*8)+(5*2)+(4*4)+(3*0)+(2*6)+(1*5)=120
120 % 10 = 0
So 138240-65-0 is a valid CAS Registry Number.
InChI:InChI=1/C15H21N3O4S.C10H11NO3/c1-7(19)12-10-5-11(13(15(21)22)18(10)14(12)20)23-9-3-4-17(6-9)8(2)16;12-9(13)6-7-11-10(14)8-4-2-1-3-5-8/h7,9-10,12,16,19H,3-6H2,1-2H3,(H,21,22);1-5H,6-7H2,(H,11,14)(H,12,13)/b16-8+;/t7-,9+,10-,12-;/m1./s1