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ANGELI'S SALT, also known as the sodium salt of nitroxylaminic acid (Na2N2O3), is a nitroxyl anion (NO–) donor that has been recognized for its unique chemical properties for over a century. It is a classic nitroxyl(N=O-) donor, and under certain conditions, it can also release NO gas. Angeli's Salt is synthesized by treating hydroxylamine hydrochloride with excess sodium hydroxide, followed by the addition of butyl nitrate to produce the salt as a white solid. It has gained attention for its potential applications in various fields due to its ability to release nitroxyl and NO.

13826-64-7

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13826-64-7 Usage

Uses

Used in Biochemical Model Studies:
ANGELI'S SALT is used as an HNO/NOdonor in biochemical model studies for its ability to spontaneously dissociate in a pH-dependent first-order process, liberating 0.54 moles of NO per mole of the parent compound. This property makes it a valuable tool for understanding the roles of nitroxyl and NO in biological systems.
Used in the Treatment of Hemolysis:
In the medical field, Sodium Oxyhyponitrite, a form of ANGELI'S SALT, is used in the treatment of hemolysis, a condition where red blood cells are destroyed and can lead to anemia and other complications. The nitroxyl and NO-releasing properties of ANGELI'S SALT contribute to its therapeutic effects in this application.
Used in Pharmaceutical Research:
ANGELI'S SALT's ability to release nitroxyl and NO has attracted interest in its potential use as a therapeutic agent in various diseases. Its physiological properties are being explored for their potential to modulate signaling pathways and exert inhibitory effects on disease progression, similar to other nitroxyl and NO-donating compounds.
Used in Drug Delivery Systems:
The development of novel drug delivery systems for ANGELI'S SALT aims to enhance its applications and efficacy in targeted treatments. Organic and metallic nanoparticles are being investigated as carriers for ANGELI'S SALT, with the goal of improving its delivery, bioavailability, and therapeutic outcomes in various medical applications.

Biochem/physiol Actions

Primary TargetNitroxyl anion (NO-) donor

Check Digit Verification of cas no

The CAS Registry Mumber 13826-64-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,8,2 and 6 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13826-64:
(7*1)+(6*3)+(5*8)+(4*2)+(3*6)+(2*6)+(1*4)=107
107 % 10 = 7
So 13826-64-7 is a valid CAS Registry Number.

13826-64-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name disodium,N-oxonitramide

1.2 Other means of identification

Product number -
Other names Sodium trioxodinitrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13826-64-7 SDS

13826-64-7Upstream product

13826-64-7Downstream Products

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