138279-28-4

Basic information

• Product Name: 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, (2,2-dimethyl-1-oxopropoxy)methyl methyl ester
• CAS NO: 138279-28-4
• Molecular Formula: C22H25Cl2NO6
• Molecular Weight: 470.35
• Mol File: 138279-28-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, (2,2-dimethyl-1-oxopropoxy)methyl methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, (2,2-dimethyl-1-oxopropoxy)methyl methyl ester(138279-28-4)
• EPA Substance Registry System: 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, (2,2-dimethyl-1-oxopropoxy)methyl methyl ester(138279-28-4)

Safety Data

• Hazardous Substances Data: 138279-28-4(Hazardous Substances Data)

Upstream product

• 138279-19-3 4-(2,3-Dichloro-phenyl)-1-methoxymethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid mono-(2,2-dimethyl-propionyloxymethyl) ester 
• 138299-11-3 bis(pivaloyloxymethyl) 4-(2,3-dichlorophenyl)-1,4-dihydro-1-(methoxymethyl)-2,6-dimethyl-3,5-pyridinedicarboxylate 
• 141600-77-3 4-(2,3-Dichloro-phenyl)-1-methoxymethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 
• 18997-19-8 Chloromethyl pivalate 
• 138279-25-1 4-(2,3-Dichloro-phenyl)-1-methoxymethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2,2-dimethyl-propionyloxymethyl) ester 5-methyl ester 

Downstream Products

• 105580-45-8 4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid monomethyl ester 

Relevant articles and documents

Process for preparing 1,4 dihydropyridine compounds

A 1,4-dihydropyridine derivative represented by formula (I): STR1 wherein X represents an alkyl group, or a group of STR2 in which R1, R2, and R3 may be the same or different and each represent a hydrogen atom, a halogen atom, a nitro group, a nitrile group, or a trifluoromethyl group; R4 represents a substituted or unsubstituted acyloxymethyl group, an alkoxycarbonyloxymethyl group, a (2-oxo-1,3-dioxolen-4 -yl)methyl group, a (5-substituted-2-oxo-1,3-dioxolen-4 -yl)methyl group, or an acyl group; R5 represents a lower alkyl group or a substituted alkyl group; and R6 represents a hydrogen atom, a lower alkoxymethyl group, or a lower acyloxymethyl group, is disclosed. The compound is stereospecifically hydrolyzed by the action of an enzyme to provide an optically active 1,4-dihydro -3-pyridinemonocarboxylic acid which is useful as an intermediate of pharmaceuticals in good optical purity and yield.