138290-92-3Relevant academic research and scientific papers
Organocatalysis in a synthetic receptor with an inwardly directed carboxylic acid
Shenoy, Siddhartha R.,Pinacho Crisostomo, Fernando R.,Iwasawa, Tetsuo,Rebek Jr., Julius
, p. 5658 - 5659 (2008/12/21)
A cavitand functionalized with a Kemp-s triacid derivative was used to catalyze the epoxide ring-opening cyclizations of 1,5-epoxyalcohols. A deep, cylindrical cavity containing electron-rich aromatic walls and an inwardly directed carboxylic acid displayed the necessary characteristics to bind different 1,5-epoxyalcohols and initiate their cyclization reactions. The reactions inside this synthetic receptor occurred in a catalytic and regioselective manner. These results highlight that the arrangement of functionality and unique solvation provided by the structured interiors of natural enzymes can be incorporated into synthetic systems having useful physical and chemical properties. Copyright
Tetracyanoethylene-hydrogen peroxide, a mild epoxidation system of olefins
Masaki,Miura,Mukai,Iwata,Oda,Itoh
, p. 686 - 688 (2007/10/03)
A reagent combination system, tetracyanoethylene-30% hydrogen peroxide, was found to epoxidize olefins efficiently in acetonitrile at room temperature in a stereospecific manner with retention of the configuration of the double bond.
Ethyl Cyanoformate/Hydrogen Peroxide and Related Combination Systems, Novel Epoxidizing Systems of Olefins
Masaki, Yukio,Miura, Tsuyoshi,Mukai, Isao,Itoh, Akichika,Oda, Hirohisa
, p. 1937 - 1940 (2007/10/02)
A combination system of ethyl cyanoformate and hydrogen peroxide was found to epoxidize olefins in a stereospecific manner at room temperature.Asymmetric epoxidation was observed with menthyl cyanoformate/hydrogen peroxide system.
