1382995-35-8

Usage

Type of compound

Ketone derivative

Structure

Substituted phenyl ring

Substituents

Chlorine, iodine, methoxy, and methyl groups

Applications

Organic synthesis and pharmaceutical research

Interest

Specific properties and potential applications to the scientific community

Functional groups

Valuable building block for the synthesis of complex organic molecules

Exploration

Potential pharmacological and industrial applications being further investigated

Upstream product

• 77-78-1 dimethyl sulfate 
• 292144-86-6 1-(5-chloro-2-hydroxy-3-iodo-4-methylphenyl)ethan-1-one 
• 74-88-4 methyl iodide 
• 28480-70-8 5'-chloro-2'-hydroxy-4'-methyl acetophenone 

Downstream Products

• 1382993-42-1 1-{3-Chloro-6-methoxy-2-methyl-5-[1-(9H-purin-6-ylamino)ethyl]phenyl}piperidin-4-ol 
• 1382995-38-1 1-[3-(1-aminoethyl)-5-chloro-2-methoxy-6-methylphenyl]piperidin-4-ol 
• 1382996-72-6 tert-butyl 3-[3-(1-aminoethyl)-5-chloro-2-methoxy-6-methylphenyl]azetidine-1-carboxylate 
• 1382996-81-7 tert-butyl 3-[3-chloro-6-methoxy-2-methyl-5-(1-{[9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl]amino}ethyl)phenyl]azetidine-1-carboxylate 
• 1382996-74-8 benzyl 3-[3-(1-aminoethyl)-5-chloro-2-methoxy-6-methylphenyl]azetidine-1-carboxylate 
• 1382996-75-9 Benzyl 3-(3-{1-[(tert-butoxycarbonyl)amino]ethyl}-5-chloro-2-methoxy-6-methylphenyl)azetidine-1-carboxylate 
• 1382996-68-0 1-[5-chloro-2-methoxy-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanone 
• 1382995-36-9 1-[5-chloro-3-(4-hydroxypiperidin-1-yl)-2-methoxy-4-methylphenyl]ethanone 
• 1426699-32-2 tert-butyl 3-{3-[1-(4-amino-5-oxopyrido[2,3-d]pyrimidin-8(5H)-yl)ethyl]5-chloro-2-methoxy-6-methylphenyl}azetidine-1-carboxylate 
• 1426699-07-1 tert-butyl 3-[3-chloro-5-(1-hydroxyethyl)-6-methoxy-2-methylphenyl]azetidine-1-carboxylate 
• 1426699-08-2 tert-butyl 3-[3-chloro-5-(1-chloroethyl)-6-methoxy-2-methylphenyl]azetidine-1-carboxylate 
• 1426699-72-0 tert-butyl 3-{3-[1-(4-amino-3-bromo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl]-5-chloro-2-methoxy-6-methylphenyl}azetidine-1-carboxylate 
• 1426700-06-2 3-(3-acetyl-5-chloro-2-methoxy-6-methylphenyl)cyclobutanone 
• 1426700-05-1 1-(5-chloro-2-methoxy-4-methyl-3-vinylphenyl)ethanone 

Relevant academic research and scientific papers

IMIDAZO [1,5-A] PYRAZINE DERIVATIVES AS PI3Kdelta INHIBITORS

Disclosed is a compound of Formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising thereof. Also disclosed is a method of treating PI3Kδ related disorders or diseases by using the c

USE OF PYRAZOLOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PI3K-DELTA RELATED DISORDERS

The present application provides methods of treating PI3Kδ related disorders using compounds of Formula I: or pharmaceutically acceptable salts thereof.

HETEROCYCLYLAMINES AS PI3K INHIBITORS

The present invention provides heterocyclylamine derivatives of Formula I: wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.

N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS

The present invention provides N-(1-(substituted-phenyl)ethyl)-9H-purin-6-amines derivatives that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for examp