1383056-73-2

Usage

Uses

Used in Pharmaceutical Synthesis:
2-(tert-butoxycarbonylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid is used as a building block for the synthesis of various pharmaceuticals due to its ability to form peptide linkages and its compatibility with protein synthesis.
Used in Biochemical Research:
In the field of biochemical research, 2-(tert-butoxycarbonylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid serves as a reagent, contributing to the understanding of molecular interactions and the development of new therapeutic approaches.
Used in Organic Synthesis:
As a reagent in organic synthesis, 2-(tert-butoxycarbonylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid is utilized for its unique reactivity, facilitating the creation of complex organic molecules and compounds.
Used in Drug Development:
2-(tert-butoxycarbonylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid is used as a precursor in the development of new drugs and therapeutics, capitalizing on its structural features to explore novel medicinal properties and applications across different health-related industries.

Upstream product

• 1260169-02-5 2-aminopyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester 
• 1260169-03-6 ethyl 2-(bis(tert-butoxycarbonyl)amino)pyrazolo[1,5-a]pyrimidine-3-carboxylate 

Downstream Products

• 1466563-97-2 C₂₄H₁₉ClN₆O₂ 
• 1466566-15-3 (S)-2-amino-N-(1-(1-oxo-2-phenyl-8-((trimethylsilyl)ethynyl)-1,2-dihydroisoquinolin-3-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 
• 1466565-45-6 C₂₆H₂₀N₆O₂ 
• 1693758-51-8 (S)-2-amino-N-(1-(8-((1-methyl-1H-pyrazol-4-yl)ethynyl)-1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 

Relevant academic research and scientific papers

Substituted heteroaryl compounds and compositions and uses thereof

The invention discloses a substituted ceteroary compound as well as a composition and an application thereof. The compound is a compound shown in a formula (I) or a stereisomer, a tautomer, a nitric oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or prodrug of the compound shown in the formula (I). The invention further discloses a pharmaceutical composition including the compound. The compound and the pharmaceutical composition are capable of adjusting the activity of the AK kinase and can be used for preventing, processing, treating and relieving the JAK-mediated disease or disorder.

SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE

The present invention provides novel heterocyclic compounds, pharmaceutical acceptable salts and formulations thereof useful in preventing, treating or lessening the severity of a JAK-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of JAK-mediated disease.

5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF

Compounds of Formula (00A) and methods of use as Janus kinase inhibitors are described herein.

PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS

A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2 and R3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical