138310-59-5

Basic information

• Product Name: 1H-Naphtho[2,3-c]pyran-5,10-dione,3,4- dihydro-1,7,9-trihydroxy-3-methyl-,(1S,- 3R)-
• CAS NO: 138310-59-5
• Mol File: 138310-59-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Naphtho[2,3-c]pyran-5,10-dione,3,4- dihydro-1,7,9-trihydroxy-3-methyl-,(1S,- 3R)- (CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Naphtho[2,3-c]pyran-5,10-dione,3,4- dihydro-1,7,9-trihydroxy-3-methyl-,(1S,- 3R)- (138310-59-5)
• EPA Substance Registry System: 1H-Naphtho[2,3-c]pyran-5,10-dione,3,4- dihydro-1,7,9-trihydroxy-3-methyl-,(1S,- 3R)- (138310-59-5)

Safety Data

• Hazardous Substances Data: 138310-59-5(Hazardous Substances Data)

Upstream product

• 233253-24-2 (S)-(+)-3,4-dihydro-7,9-dihydroxy-3-methyl-1H-naphtho[2,3-c]pyran-5,10-dione 
• 444805-53-2 (1R,3S)-(+)-5,7-dibromo-1-hydroxy-8-methoxy-3-methyl-3,4-dihydro-1H-2-benzopyran 
• 445486-49-7 (S)-(+)-5-bromo-8-hydroxy-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one 
• 233253-20-8 (S)-(+)-5,7-dibromo-8-methoxy-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one 
• 233253-19-5 (S)-(+)-5,7-dibromo-8-hydroxy-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one 
• 233253-21-9 (S)-(+)-5,7-dibromo-8-methoxy-3-methyl-3,4-dihydro-1H-2-benzopyran 
• 233253-22-0 (S)-(+)-5,7-dibromo-8-hydroxy-3-methyl-3,4-dihydro-1H-2-benzopyran 
• 233253-23-1 (S)-(+)-7-bromo-3-methyl-3,4-dihydro-1H-2-benzopyran-5,8-dione 
• 480-33-1 (S)-mellein 

Relevant articles and documents

Synthesis and absolute stereochemistry of thysanone

The structure and absolute stereochemistry of thysanone 3, a fungal benzoisochromanquinone with potent human rhinovirus 3C-protease inhibitory activity, is established by the total synthesis of its antipode 1 from (S)- propylene oxide.

Enantioselective synthesis of the 3C-protease inhibitor (-)-thysanone by a Staunton-Weinreb annulation strategy

The total synthesis of (-)-thysanone is described. The key step involves the addition of an o-toluate anion to a lactone to create the naphthopyran framework (Staunton-Weinreb annulation). This synthesis further confirms the absolute stereochemistry of th