1383120-29-3

Upstream product

• 98684-05-0 methyl (9R,14R)-14-(2-((tert-butoxycarbonyl)amino)acetamido)-9-(methoxycarbonyl)-2,2-dimethyl-4,7-dioxo-3-oxa-11,12-dithia-5,8-diazapentadecan-15-oate 
• 820239-42-7 benzyl N-[(1S)-2-(1H-1,2,3-benzotriazol-1-yl)-1-methyl-2-oxoethyl]carbamate 
• 1361315-49-2 GABA-L-Phe-Gly-L-Cys(S-Cbz-L-Ala)-OCH₃ hydrochloride 
• 1361315-48-1 Boc-GABA-L-Phe-Gly-L-Cys(S-Cbz-L-Ala)-OCH₃ 
• 1361315-47-0 Boc-GAB-L-Phe-Gly-L-Cys-OCH₃ 
• 1361315-46-9 (Boc-GABA-L-Phe-Gly-L-Cys-OCH₃)2 
• 1361315-45-8 Boc-GABA-L-Phe-OH 

Relevant academic research and scientific papers

Long-range intramolecular s → N acyl migration: A study of the formation of native peptide analogues via 13-, 15-, and 16-membered cyclic transition states

The intramolecular long-range S → N acyl migration via 13-, 15-, and 16-membered cyclic transition states to form native tetra- and pentapeptide analogues was studied on S-acylcysteine peptides containing β- or γ-amino acids. The pH-dependency study of the acyl migration via a 15-membered cyclic transition state indicated that the reaction is favored at a pH range from 7.0 to 7.6. Experimental observations are supported by structural and computational investigations.