138319-92-3

Upstream product

• 115822-50-9 (R)-2-<(tert-Butoxycarbonyl)amino>-3-hydroxy-2-N,3-O-isopropylidene-1-(1,3-thiazol-2-yl)-1-propanone 
• 145532-48-5 (1S,2R)-2-<(tert-Butoxycarbonyl)amino>-3-hydroxy-2-N,3-O-isopropylidene-1-(1,3-thiazol-2-yl)-1-propanol 
• 108149-60-6 methyl [(4R)-3-(tert-butoxycarbonyl)-2,2-dimethyl-1,3-oxazolidin-4-yl]carboxylate 
• 138319-91-2 ((1R,2S)-2-Hydroxy-1-hydroxymethyl-2-thiazol-2-yl-ethyl)-carbamic acid tert-butyl ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 115822-50-9 (S)-2-<(N-tert-butoxycarbonyl-2,2-dimethyl-1,3-oxazolidin-4-yl)carbonyl>-1,3-thiazole 
• 95715-86-9 (S)-2,2-dimethyl-oxazolidine-3,4-dicarboxylic acid 3-tert-butyl ester 4-methyl ester 
• 138319-91-2 (1R,2S)-2-tert-butoxycarbonylamino-1-(1,3-thiazol-2-yl)propane-1,3-diol 
• 115822-49-6 (R)-2-<<(4S)-tert-butoxycarbonyl-2,2-dimethyl-1,3-oxazolidin-4-yl>-hydoxymethyl>-1,3-thiazole 

Downstream Products

• 138319-96-7 (4S,5R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-5-thiazol-2-yl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 138319-96-7 (1S,2R)-2-<(tert-Butoxycarbonyl)amino>-3-<(tert-butyldiphenylsilyl)oxy>-1-hydroxy-2-N,1-O-isopropylidene-1-(1,3-thiazol-2-yl)propane 
• 138319-97-8 3-<(tert-Butoxycarbonyl)amino>-4-O-(tert-butyldiphenylsilyl)-3-deoxy-3-N,2-O-isopropylidene-D-threose 

Relevant academic research and scientific papers

Total Synthesis of (+)-Galactostatin. An Illustration of the Utility of the Thiazole-Aldehyde Synthesis

The natural aza sugar (+)-galactostatin (+)-1 has been prepared from D-serine by sequential installation of chiral 1C and 2C units employing thiazole-based reagents.Thus, the D-serine-derived methyl ester 3 was transformed by 2-thiazolyllithium (4) into t

Stereocontrolled Total Synthesis of Galactostasin from Serine

An efficient stereoselective total synthesis of (-)-galactostasin (-)-1 from N-tert-butoxycarbonyl-2,3-isopropylidene L-serine methyl ester (21percent overall yield) is described via thiazole intermediates serving as protected aldehydes; the parallel synt