1383232-09-4

Basic information

• Product Name: N-(4-methoxyphenyl)-N-methyl-2-aminopyridine
• Synonyms: N-(4-methoxyphenyl)-N-methyl-2-aminopyridine
• CAS NO: 1383232-09-4
• Molecular Weight: 214.267
• Mol File: 1383232-09-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(4-methoxyphenyl)-N-methyl-2-aminopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxyphenyl)-N-methyl-2-aminopyridine(1383232-09-4)
• EPA Substance Registry System: N-(4-methoxyphenyl)-N-methyl-2-aminopyridine(1383232-09-4)

Safety Data

• Hazardous Substances Data: 1383232-09-4(Hazardous Substances Data)

Upstream product

• 1352965-27-5 N-methyl-N-(4-methoxyphenyl)pyridine-2-sulfonamide 
• 104-94-9 4-methoxy-aniline 
• 78644-78-7 N-(4-methoxyphenyl)pyridin-2-amine 
• 74-88-4 methyl iodide 
• 109-04-6 2-bromo-pyridine 

Downstream Products

• 1383231-76-2 N-methyl-N-(2-triisopropylsilylethynyl-4-methoxyphenyl)-2-aminopyridine 

Relevant articles and documents

Nickel-Catalyzed Intramolecular Desulfitative C - N Coupling: A Synthesis of Aromatic Amines

A nickel-catalyzed intramolecular C - N coupling reaction via SO2 extrusion is presented. The use of a catalytic amount of BPh3 allows the transformation to take place under much milder conditions (60 °C) than previously reported C - N coupling reactions by CO or CO2 extrusion (160-180 °C). In addition, this method displays good functional group tolerance and versatility, as it can be applied to the synthesis of dialkyl aryl amines, alkyl diaryl amines, and triaryl amines. The robustness of the desulfitative C - N coupling is demonstrated by three high-yielding gram-scale reactions.

Palladium-catalyzed oxidative alkynylation of arene C-H bond using the chelation-assisted strategy

Palladium-catalyzed alkynylation of arene C-H bonds with (triisopropylsilyl)acetylene was developed for the first time under oxidative conditions in the present study. Among various type of directing groups examined, the N-phenyl-2-aminopyridine skeleton was shown to be most effective and selective for the Pd-catalyzed direct alkynylation reaction, and the desired alkynylated products were obtained in moderate to good yields.