1383232-16-3Relevant academic research and scientific papers
Palladium-catalyzed oxidative alkynylation of arene C-H bond using the chelation-assisted strategy
Kim, Seok Hwan,Park, Sae Hume,Chang, Sukbok
supporting information; experimental part, p. 5162 - 5166 (2012/07/31)
Palladium-catalyzed alkynylation of arene C-H bonds with (triisopropylsilyl)acetylene was developed for the first time under oxidative conditions in the present study. Among various type of directing groups examined, the N-phenyl-2-aminopyridine skeleton was shown to be most effective and selective for the Pd-catalyzed direct alkynylation reaction, and the desired alkynylated products were obtained in moderate to good yields.
