1383232-38-9Relevant academic research and scientific papers
Synthesis of Amidines from Amides Using a Nickel-Catalyzed Decarbonylative Amination through CO Extrusion Intramolecular Recombination Fragment Coupling
Liu, Xiangqian,Yue, Huifeng,Jia, Jiaqi,Guo, Lin,Rueping, Magnus
supporting information, p. 11771 - 11775 (2017/09/07)
A catalytic synthesis of amidines from amides has been established for the first time. The newly developed CO extrusion recombination process takes advantage of an inexpensive nickel(II) catalyst and provides the corresponding amidines with high efficiency. The intramolecular fragment coupling shows excellent chemoselectivity, starts from readily available amides, and provides a valuable alternative amidine synthesis protocol.
Palladium-catalyzed oxidative alkynylation of arene C-H bond using the chelation-assisted strategy
Kim, Seok Hwan,Park, Sae Hume,Chang, Sukbok
, p. 5162 - 5166 (2012/07/31)
Palladium-catalyzed alkynylation of arene C-H bonds with (triisopropylsilyl)acetylene was developed for the first time under oxidative conditions in the present study. Among various type of directing groups examined, the N-phenyl-2-aminopyridine skeleton was shown to be most effective and selective for the Pd-catalyzed direct alkynylation reaction, and the desired alkynylated products were obtained in moderate to good yields.
