138329-68-7Relevant academic research and scientific papers
FUSED HETEROTRICYCLIC IMIDES WITH PSYCHOTROPIC ACTIVITY AND INTERMEDRATES THEREOF
-
, (2008/06/13)
There are disclosed compounds of the formula STR1 wherein R 1 and R 2 taken together represent STR2 R 3 and R 4 are hydrogen; R 5 is 2-pyridinyl, 2-pyrazinyl, 2-pyrimidinyl, 3-pyridazinyl or any of the foregoing R 5 moieties substituted by lower alkyl, lower alkoxy, halo lower alkyl, cyano, nitro or halo;X, Y and Z are, independently, N, S, O, NR 6, SO, SO 2, CR. sup.6 or CH 2 ;A is lower alkylene, O or S; R 6 is hydrogen, lower alkyl, aryl, aralkyl;m is 3-7;and the pharmaceutically acceptable salts thereof, and their use as antipsychotic/-anxiolytic agents having a low liability for extrapyramidal side effects.
