1383291-91-5Relevant academic research and scientific papers
Grob fragmentation of 2-azabicyclo[2.2.2]oct-7-ene: Tool for the stereoselective synthesis of polysubstituted piperidines
Lemonnier, Gerald,Charette, Andre B.
, p. 5832 - 5837 (2012)
The Grob fragmentation of azabicyclo[2.2.2]octene leads to a dihydropyridinium intermediate. This highly reactive species reacts with a variety of organocuprates and other soft nucleophiles in a regioselective manner, allowing for the rapid and stereosele
