138331-61-0

Upstream product

• 131533-36-3 (2R,3S)-3-[(S)-(Dimethyl-phenyl-silanyl)-phenyl-methyl]-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid methyl ester 
• 103-26-4 Methyl cinnamate 
• 144539-95-7 (2R,3R)-1-[Bis-(4-methoxy-phenyl)-methyl]-3-[(R)-(dimethyl-phenyl-silanyl)-phenyl-methyl]-4-oxo-azetidine-2-carboxylic acid methyl ester 
• 144452-46-0 β-Dimethylphenylsilyl-β-phenyl propanoyl chloride 
• 3839-31-4 dimethyl(phenyl)silyllithium 

Downstream Products

• 144452-47-1 (2S,3R)-2-Amino-3-[(S)-(dimethyl-phenyl-silanyl)-phenyl-methyl]-succinic acid dimethyl ester 
• 138331-65-4 Methyl 2(S*)-(benzoylamino)-4(S*)-hydroxy-3(R*)-(methoxycarbonyl)-4-phenylbutanoate 
• 138331-63-2 (2R,3S)-2-Benzoylamino-3-[(R)-(dimethyl-phenyl-silanyl)-phenyl-methyl]-succinic acid dimethyl ester 
• 144452-47-1 (2R,3R)-2-Amino-3-[(R)-(dimethyl-phenyl-silanyl)-phenyl-methyl]-succinic acid dimethyl ester 
• 144452-49-3 (2R,3R)-2-Benzyl-3-tert-butoxycarbonylamino-succinic acid dimethyl ester 
• 144452-48-2 (2R,3R)-2-tert-Butoxycarbonylamino-3-[(R)-(dimethyl-phenyl-silanyl)-phenyl-methyl]-succinic acid dimethyl ester 

Relevant academic research and scientific papers

A concise stereoselective approach to β-Alkylaspartates from β-Lactams via [2 + 2] cycloaddition reaction of ketenes to glyoxylic ester-derived imines

syn β-Alkyl aspartates were obtained with high stereoselectivities from cis 4-alkoxycarbonyl-β-lactams prepared via [2 + 2] cycloaddition reaction of monoalkylketenes and glyoxalate derived imines.

Formation of 3-azetidin-2-ones: Stereocontrolled Formal Approach to (+/-)-Thienamycin and (+/-)-β-(Hydroxyalkyl)aspartic Acid Derivatives

Reaction between (+/-)-β-(dimethylphenylsilyl)alkanoyl chlorides and imines of glyoxylic esters provided a route to (+/-)-cis-3--4-alkoxycarbonyl β-lactams, while addition of the Fleming's silylcuprate reagent to methyl crot