1383324-89-7Relevant academic research and scientific papers
Palladium-catalyzed selective C-H benzylation towards functionalized azoles with a quaternary carbon center
Xie, Pan,Huang, Hanmin,Xie, Yinjun,Guo, Shengmei,Xia, Chungu
, p. 1692 - 1700 (2012)
The direct C-H benzylation of azoles with benzyl chlorides proceeds efficiently, via sequential cleavage of one sp2 C-H bond and two sp3 C-H bonds in the presence of a palladium catalyst, to generate a wide range of tribenzylated azoles with a quaternary carbon center efficiently. The same catalyst could also promote the mono- and di-benzylation reactions through fine turning of the base and reaction conditions. Copyright
