138336-44-4

Upstream product

• 5292-43-3 bromoacetic acid tert-butyl ester 
• 28075-68-5 (1R)-cis-hemicaronaldehydic acid 
• 130051-20-6 tert-Butyl 2-(tert-Butylsulfonyl)acetate 
• 49827-07-8 tert-butyl α-tert-butylthioacetate 
• 13826-35-2 3-Phenoxybenzyl alcohol 
• 130051-19-3 (1R,1α,3α)-6,6-Dimethyl-4-<2-tert-butoxy-2-oxo-1-(tert-butylsulfonyl)ethyl>-3-oxabicyclo<3.1.0>hexan-2-one 

Downstream Products

• 138383-26-3 (1R,3S)-3-[(1R,2R)-2-tert-Butoxycarbonyl-1-((R)-methoxysulfinyl)-2-(2-methyl-propane-2-sulfonyl)-ethyl]-2,2-dimethyl-cyclopropanecarboxylic acid 3-phenoxy-benzyl ester 
• 138336-38-6 (1R,3S)-3-[(1R,2R)-2-tert-Butoxycarbonyl-1-((S)-methoxysulfinyl)-2-(2-methyl-propane-2-sulfonyl)-ethyl]-2,2-dimethyl-cyclopropanecarboxylic acid 3-phenoxy-benzyl ester 
• 81449-75-4 <1R,1α,3α(Z)>-(3-Phenoxyphenyl)methyl 2,2-Dimethyl-3-(3-tert-butoxy-3-oxo-1-propenyl)cyclopropanecarboxylate 
• 130144-15-9 <1R,1α,3α(E)>-(3-Phenoxyphenyl)methyl 2,2-Dimethyl-3-(3-tert-butoxy-3-oxo-1-propenyl)cyclopropanecarboxylate 

Relevant academic research and scientific papers

A New Way toward Z α,β Unsaturated Esters: A Pyrethroid Application

Use of the stereospecific condensation of β carbalkoxysulfones with aldehydes, followed by the stereospecific reduction of the afforded sulfonyl acrylate with sodium dithionite allows us to propose this method as a new way to prepare Z α,β unsaturated esters.Steric hindrance seems to be the reason for the selectivity of the reduction and the mechanism was proved, by X-ray of an intermediate, to be a cis Michael addition of HSO2-, followed by an anti elimination of SO2 and the sulfinate group.This method discovered in the pyrethroid series for the synthesis of acrinathrin 1 could have general application.