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TERT-BUTYL 8-CHLORO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE is a chemical compound characterized by the molecular formula C16H20ClNO2. It features a carboxylate ester with a tert-butyl group, a chloro substituent, and a dihydroisoquinoline ring. TERT-BUTYL 8-CHLORO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE holds potential applications in various fields, including pharmaceutical and agrochemical industries, as well as academic research. Due to its chemical nature, it is crucial to handle TERT-BUTYL 8-CHLORO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE with care and to implement proper safety measures during its use.

138350-93-3

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138350-93-3 Usage

Uses

Used in Pharmaceutical Industry:
TERT-BUTYL 8-CHLORO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a building block in the development of new drugs, potentially contributing to the creation of medications for different therapeutic areas.
Used in Agrochemical Industry:
In the agrochemical sector, TERT-BUTYL 8-CHLORO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE is utilized as a precursor in the production of agrochemicals. Its properties may be harnessed to develop new pesticides, herbicides, or other agricultural chemicals that can improve crop protection and yield.
Used in Academic Research:
TERT-BUTYL 8-CHLORO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE serves as a valuable compound in academic research settings. Researchers can use it to study the effects of structural modifications on chemical properties and reactivity, furthering the understanding of organic chemistry and its applications in various scientific disciplines.

Check Digit Verification of cas no

The CAS Registry Mumber 138350-93-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,3,5 and 0 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 138350-93:
(8*1)+(7*3)+(6*8)+(5*3)+(4*5)+(3*0)+(2*9)+(1*3)=133
133 % 10 = 3
So 138350-93-3 is a valid CAS Registry Number.

138350-93-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 8-chloro-3,4-dihydro-1H-isoquinoline-2-carboxylate

1.2 Other means of identification

Product number -
Other names TERT-BUTYL 8-CHLORO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:138350-93-3 SDS

138350-93-3Downstream Products

138350-93-3Relevant academic research and scientific papers

Heteroatom-directed lateral lithiation: Synthesis of isoquinoline derivatives from N-(tert-butoxycarbonyl)-2-methylbenzylamines

Clark,Jahangir,Langston

, p. 23 - 30 (2007/10/02)

Methodology for the preparation of isoquinoline derivatives from N-(tert-butoxycarbonyl)-2-methylbenzylamines (1) was developed. Conversion of 1 to the dilithio species followed by condensation with DMF afforded Boc-3-hydroxy-1,2,3,4-tetrahydroisoquinolin

PREPARATION OF TETRAHYDROISOQUINOLINES FROM N-(TERT-BUTOXYCARBONYL)-2-METHYLBENZYLAMINES

Clark, Robin D.,Jahangir

, p. 1699 - 1703 (2007/10/02)

Dilithiation of N-(tert-butoxycarbonyl)-2-methylbenzylamine (1a) followed by treatment with N,N-dimethylformamide affords 2-(tert-butoxycarbonyl)-3-hydroxy-tetrahydroisoquinoline (3a).Dehydration and reduction of 3a afford BOC-tetrahydroisoquinoline (5a).The methodology is also applicable to synthesis of chloro and fluoro substituted tetrahydroisoquinolines (5b,c), 3 and 4-substituted derivatives (8,10), and the hexahydro-2H-benzoquinolizine ring system (13).

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