1383531-79-0

Basic information

• Product Name: C₁₆H₁₉NO₂
• Synonyms: C₁₆H₁₉NO₂
• CAS NO: 1383531-79-0
• Molecular Weight: 257.332
• Mol File: 1383531-79-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₉NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₉NO₂(1383531-79-0)
• EPA Substance Registry System: C₁₆H₁₉NO₂(1383531-79-0)

Safety Data

• Hazardous Substances Data: 1383531-79-0(Hazardous Substances Data)

Upstream product

• 931-53-3 Cyclohexyl isocyanide 
• 140-10-3 (E)-3-phenylacrylic acid 

Downstream Products

• 6750-98-7 (E)-N-cyclohexylcinnamamide 
• 120230-91-3 ((1S,2R,3R,4R)-3-Phenyl-bicyclo[2.2.2]oct-5-en-2-yl)-methanol 

Relevant articles and documents

Enhancing the scope of the Diels-Alder reaction through isonitrile chemistry: Emergence of a new class of acyl-activated dienophiles

α,β-Unsaturated imides, formylated at the nitrogen atom, comprise a new and valuable family of dienophiles for servicing Diels-Alder reactions. These systems are assembled through extension of recently discovered isonitrile chemistry to the domain of α,β-unsaturated acids. Cycloadditions are facilitated by Et2AlCl, presumably via chelation between the two carbonyl groups of the N-formyl amide. Applications of the isonitrile/Diels-Alder logic to the IMDA reaction, as well as methodologies to modify the N-formyl amide of the resultant cycloaddition product, are described. It is expected that this easily executed chemistry will provide a significant enhancement for application of Diels-Alder reactions to many synthetic targets.