1383549-88-9Relevant academic research and scientific papers
Facile synthesis of 3-substituted isoquinolines derivatives via microwave-assisted tandem three-component coupling cyclization
Lin, Long,Wu, Qiongyou,Huang, Shaowei,Yang, Guangfu
, p. 1075 - 1082 (2012)
A novel three-component reaction of o-bromobenzaldehyde, terminal alkynes and tert-butyl amine has been established, which proceeded smoothly to give 3-substituted isoquinolines in good yields in the presence of palladium/copper catalysts under microwave irradiation.
