138355-90-5

Upstream product

• 138456-91-4 6,7-O,O-demethylene-4'-O-demethylepipodophyllotoxin 
• 6559-91-7 4'-demethylepipodophyllotoxin 
• 100-01-6 4-nitro-aniline 
• 18651-67-7 6,7-O,O-demethylene-6,7-O,O-dimethylpodophyllotoxin 
• 1178-09-2 (3aR,4S,9R,9aR)-4-hydroxy-6,7-dimethoxy-9-(3,4,5-trimethoxyphenyl)-3a,4,9,9a-tetrahydronaphtho[2,3-c]furan-1(3H)-one 

Relevant academic research and scientific papers

Anti-AIDS agents. Part 61: Anti-HIV activity of new podophyllotoxin derivatives

A series of novel podophyllotoxin derivatives containing structural modifications at C-4 (7-14), C-4′ (16-17), and the methylenedioxy A-ring (23-28) was synthesized and tested for inhibition of HIV replication. Four of these compounds (25-28) were previou

Antitumor agents. 124. New 4β-substituted aniline derivatives of 6,7-O,O- demethylene-4'-O-demethylpodophyllotoxin and related compounds as potent inhibitors of human DNA topoisomerase II

A series of 6,7-O,O-demethylene-4'-O-demethyl-4β-(substituted anilino)-4- desoxypodophyllotoxins (18-23), 6,7-O,O-demethylene-6,7-O,O-dimethyl-4'-O- demethyl-4β-(substituted anilino)-4-desoxypodophyllotoxins (28-31), and their corresponding 4'-O-methyl an