1383577-08-9Relevant academic research and scientific papers
Phosphine-catalyzed domino reaction for the synthesis of conjugated 2,3-dihydrofurans from allenoates and Nazarov reagents
Xie, Peizhong,Lai, Wenqing,Geng, Zhishuai,Huang, You,Chen, Ruyu
supporting information; experimental part, p. 1533 - 1537 (2012/07/30)
A new domino reaction for Nazarov reagents: An efficient approach was developed for the construction of highly functionalized conjugated 2,3-dihydrofuran skeletons. Nazarov reagents were used for the first time in a phosphine-catalyzed domino reaction and successfully used to construct five-membered ring compounds using alcohol as the solvent. DFT calculations indicate that alcohol is essential for the catalysis of the [1,2]-proton transfer. Copyright
