1383577-44-3

Basic information

• Product Name: prop-2-yn-1-yl 2-(4-([(2-azidophenyl)carbonyloxy]methyl)-1H-1,2,3-triazol-1-yl)benzoate
• Synonyms: prop-2-yn-1-yl 2-(4-([(2-azidophenyl)carbonyloxy]methyl)-1H-1,2,3-triazol-1-yl)benzoate
• CAS NO: 1383577-44-3
• Molecular Weight: 402.369
• Mol File: 1383577-44-3.mol

Chemical Properties

• CAS DataBase Reference: prop-2-yn-1-yl 2-(4-([(2-azidophenyl)carbonyloxy]methyl)-1H-1,2,3-triazol-1-yl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: prop-2-yn-1-yl 2-(4-([(2-azidophenyl)carbonyloxy]methyl)-1H-1,2,3-triazol-1-yl)benzoate(1383577-44-3)
• EPA Substance Registry System: prop-2-yn-1-yl 2-(4-([(2-azidophenyl)carbonyloxy]methyl)-1H-1,2,3-triazol-1-yl)benzoate(1383577-44-3)

Safety Data

• Hazardous Substances Data: 1383577-44-3(Hazardous Substances Data)

Upstream product

• 118-48-9 isatoic anhydride 
• 90923-99-2 propargyl anthranilate 
• 1383577-49-8 prop-2-yn-1-yl 2-(4-([(2-aminophenyl)carbonyloxy]methyl)-1H-1,2,3-triazol-1-yl)benzoate 
• 1383577-47-6 2-(4-([(2-aminophenyl)carbonyloxy]methyl)-1H-1,2,3-triazol-1-yl)benzoic acid 

Relevant articles and documents

Propargyl anthranilate derivatives and their application in the synthesis of rings containing 1,2,3-triazolo motifs

Propargyl anthranilate, a simple and less studied molecule with several reactive sites, is widely applicable in organic synthesis. An optimized synthesis of this compound and its derivatives and the preparation of azide derivatives are described. The optimized process of the known intramolecular cyclization is described, and the unknown intermolecular cyclizations of these azido derivatives and formation of a macrocycle are discussed.

Study of direct macrocycle formation via the cyclisation of propargyl 2-azidobenzoate

Macrocycles were synthesised via the cyclisation of propargyl 2-azidobenzoate using 'click' chemistry. An LC/MS-based method for the separation of macrocycles is described. In the present work, the influence of various catalysts and reaction conditions on

Synthesis of macrocycles containing 1,2,3-triazole motifs

A new procedure for the preparation of macrocycles containing 1,2,3-triazole motifs is developed. The macrocyclic precursor is constructed by repetition of a series of steps which include cycloaddition of an azide with an alkyne, alkylation of a carboxylic acid with propargyl bromide and formation of an azide from an amino group. The order of the steps and the size of the connected fragments are determined by the desired ring size. Chromatographic purification techniques for the poorly soluble final products are also described. Georg Thieme Verlag Stuttgart · New York.