1383659-09-3

Basic information

• Product Name: 6-methyl-4-(morpholin-4-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine
• CAS NO: 1383659-09-3
• Molecular Weight: 295.344
• Mol File: 1383659-09-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-methyl-4-(morpholin-4-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-4-(morpholin-4-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine(1383659-09-3)
• EPA Substance Registry System: 6-methyl-4-(morpholin-4-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine(1383659-09-3)

Safety Data

• Hazardous Substances Data: 1383659-09-3(Hazardous Substances Data)

Upstream product

• 5334-43-0 5-Amino-4-cyano-1-phenylpyrazole 
• 110-91-8 morpholine 
• 23121-14-4 4-chloro-6-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 91974-63-9 6-methyl-1-phenyl-1H-pyrazolo<3,4-d>pyrimidine-4(5H)-one 
• 50427-77-5 5-amino-1-phenyl-1H-pyrazole-4-carboxamide 

Relevant articles and documents

Synthesis of novel 2-alkyl-4-substituted-amino-pyrazolo[3,4-d]pyrimidines as new leads for anti-bacterial and anti-cancer activity

Treatment of 6-alkyl-1-phenyl-4-chloro-(1H)-pyrazolo[3,4-d]pyrimidines, with different amines afforded a series of compounds whose identity and purity were confirmed by spectral and analytical means. The compounds were tested for antibacterial activity against four organisms viz. Staphylococcus aureus (Gram positive), S. epidermidis (Gram positive), Bacillus subtilis (Gram positive), Escherichia coli (Gram negative) using amoxicillin as standard control. Compounds 4d, 6b, 6c have shown best antibacterial activity in the series. The antiproliferative activity was tested against human skin cancer cell line G361. The compounds 3d, 4d, 5b, 5d, 5e, 6c, 7a were found to be the best of the series and showed the activity at micromolar concentration.