1383677-80-2Relevant academic research and scientific papers
A novel one-pot synthesis of 2-arylpyrazoloquinolinone derivatives
Chang, En-Chiuan,Wen, Ya-Lan,Chang, Chun-Hsi,Shen, Yun-Hwei,Wen, Shaw-Bing,Yeh, Mou-Yung,Wong, Fung Fuh
, p. 5920 - 5924 (2012)
Two regioisomers of 2-arylpyrazolo[3,4-c]quinolin-4(5H)-ones and 2-arylpyrazolo[4,3-c]quinolin-4(5H)-ones were synthesized by utilizing 3-arylsydnones, ethyl 3-bromopropynoate, and 2-aminophenylboronic acid pinacol ester in presence of catalytic agent Pd(PPh3)4. This efficient one-pot synthesis methodology involved 1,3-dipolar cycloaddition, Suzuki coupling reaction, and intramolecular cyclization three sequence steps.
