1383715-79-4Relevant academic research and scientific papers
Microwave accelerated Glaser-Hay macrocyclizations at high concentrations
Bédard, Anne-Catherine,Collins, Shawn K.
, p. 6420 - 6422 (2012/07/14)
Efficient macrocyclization can be conducted at high concentrations employing microwave irradiation and a phase separation strategy. The rate of the Glaser-Hay macrocyclization is accelerated using microwave irradiation and reaction times decreased from 48 h to 1-6 h, depending on the nature of the substrate. Macrocyclization concentrations could be increased up to 0.1 M compared to traditional concentrations (0.2 mM).
