138375-81-2Relevant academic research and scientific papers
Fast synthesis of complex enantiopure heterocyclic scaffolds by a tandem sequence of simple transformations on α-hydroxyaldehydes
Cannillo, Alexandre,Norsikian, Stephanie,Retailleau, Pascal,Dau, Marie-Elise Tran Huu,Iorga, Bogdan I.,Beau, Jean-Marie
, p. 9127 - 9131 (2013)
Two tandems are faster than one! Properly sequenced reactions initiated by the Petasis aminoalcohol synthesis from boronic acids, diallylamine, and α-hydroxyaldehydes, including free aldoses, leads to rapid construction of complex enantiopure structures (see scheme). Copyright
Palladium catalysed tandem cyclisation-anion capture. Part 8: Cascade hydrostannylation-cyclisation-anion capture and cascade hydroboration-cyclisation-anion capture on solid phase
Grigg, Ronald,MacLachlan, William S,MacPherson, David T,Sridharan, Visuvanathar,Suganthan, Selvaratnam
, p. 10335 - 10345 (2007/10/03)
Up to four bonds and five stereocentres are created, in five component processes (five point diversity), utilising resin bound aryl iodides by hydroboration or hydrostannylation of alkynes, followed by cyclisation-anion capture involving Suzuki or Stille reactions. Three small libraries were prepared to validate the chemistry.
