138384-04-0Relevant articles and documents
Benzazepinone calcium channel blockers. 4. Structure-activity overview and intracellular binding site
Kimball,Floyd,Das,Hunt,Krapcho,Rovnyak,Duff,Lee,Moquin,Turk,Hedberg,Moreland,Brittain,McMullen,Normandin,Cucinotta
, p. 780 - 793 (2007/10/02)
We have synthesized a series of benzazepinones (2) in order to determine the structure-activity relationships (SAR) for calcium channel blockers related to diltiazem. A prerequisite for calcium channel blocking activity in vitro and in vivo is the presenc